Page 44 - 《华中农业大学学报(自然科学版)》2022年第5期
P. 44

38                                 华 中 农 业 大 学 学 报                                    第 41 卷

               标记分析,能够准确鉴定出与表型和抗性性状相关                          [8] XIA E H,TONG W,HOU Y,et al.The reference genome of tea
               的许多遗传变异位点和目的基因,发现参与抗性调                               plant and resequencing of 81 diverse accessions provide insights
                                                                    into its genome evolution and adaptation[J]. Molecular plant,
               控的新遗传变异位点和新基因。总的来说,由于
                                                                    2020,13(7):1013-1026.
               GWAS 能够为茶树育种提供分子标记,可以加快茶                        [9] ZHANG Q J,LI W,LI K,et al.The chromosome-level reference
               树抗性基因鉴定的研究进程,并最终提高茶树抗性                               genome of tea tree unveils recent bursts of non-autonomous LTR
                                                                    retrotransposons in driving genome size evolution[J].Molecular
               品种的育种效率,基于茶树抗性的 GWAS 将会逐渐
                                                                    plant,2020,13(7):935-938.
               成为茶树育种研究的热点。                                    [10] WANG X C,FENG H,CHANG Y X,et al.Population sequenc⁃
                   一般来说,表型性状的变异有限,而大量代谢物                            ing enhances understanding of tea plant evolution[J/OL].Nature
                                                                    communications,2020,11(1):4447[2022-03-07].https://doi.
               的含量存在巨大的差异。GWAS 鉴定的作物表型性
                                                                    org/10.1038 /s41467-020-18228-8.
               状 QTL 往往具有中或低等效应           [57] ,部分原因可能是        [11] ZHANG W Y,ZHANG Y J,QIU H J,et al.Genome assembly
               基于目标表型的有限变异。调控代谢物积累的遗传                               of wild tea tree dasz reveals pedigree and selection history of tea
                                                                    varieties[J/OL]. Nature communications,2020,11(1):3719
               变异更容易与全基因组进行关联分析,mGWAS
                                                                    [2022-03-07].https://doi.org/10.1038/s41467-020-17498-6.
              (metabolome-based genome-wide association study)
                                                               [12] WANG P J,YU J X,JIN S,et al.Genetic basis of high aroma
               在水稻、玉米、番茄等作物中已经被广泛使用,鉴定                              and stress tolerance in the oolong tea cultivar genome[J/OL].
               出与独角金内酯、类黄酮等代谢物相关的调控基                                Horticulture research,2021,8(1):107[2022-03-07]. https://
                                                                    doi.org/10.1038/s41438-021-00542-x.
               因 [23,58-59] 。此外,结合转录组、代谢组和基因组的多
                                                               [13] ERSOZ E S,YU H M,BUCKLER E S.Applications of linkage
               组学关联分析已经在拟南芥、番茄等植物中普遍应                               disequilibrium and association mapping in crop plants[M].Dor⁃
               用,鉴定出与植物非生物胁迫和调控类黄酮合成相                               drecht:Springer ,2008:97-119.
                                                               [14] 赵振卿,顾宏辉,盛小光,等 . 作物数量性状位点研究进展及其
               关的基因    [59-60] 。茶树多组学 GWAS将会成为今后研
                                                                    育种应用[J]. 核农学报,2014,28(9):1615-1624.ZHAO Z Q,
               究的热点。                                                GU H H,SHENG X G,et al.Advances and applications in crop
                                                                    quantitative trait locus[J].Journal of nuclear agricultural scienc⁃
                                                                    es,2014,28(9):1615-1624(in Chinese with English abstract).
               参考文献 References                                 [15] FREEMAN J L,PERRY G H,FEUK L,et al. Copy number
                                                                    variation:new insights in genome diversity[J].Genome research,
              [1] 叶乃兴 . 茶学研究法[M]. 北京:中国农业出版社,2011.YE N
                                                                    2006,16(8):949-961.
                    X.Research methods of tea science[M].Beijing:China Agricul⁃
                                                               [16] KORTE A,FARLOW A. The advantages and limitations of
                    ture Press,2011(in Chinese).
                                                                    trait analysis with GWAS:a review[J].Plant methods,2013,9
              [2] ZHANG X T,CHEN S,SHI L Q,et al.Haplotype-resolved ge⁃
                                                                    (4):749-764.
                    nome assembly provides insights into evolutionary history of the  [17] ZUK O,HECHTER E,SUNYAEV S R,et al.The mystery of
                    tea plant Camellia sinensis[J/OL]. Nature genetics,2021,53  missing heritability:genetic interactions create phantom heritabili⁃
                   (6):1250[2022-03-07]. https://doi. org/10.1038/s41588-021-  ty[J].PNAS,2012,109(4):1193-1198.
                    00895-y.                                   [18] WEI W H,HEMANI G,HALEY C S.Detecting epistasis in hu⁃
              [3] LIN X H,SUN D W.Recent developments in vibrational spectro⁃  man complex traits[J].Nature reviews genetics,2014,15(11):
                    scopic techniques for tea quality and safety analyses[J].Trends in  722-733.
                    food science & technology,2020,104:163-176.  [19] WINHAM S J,BIERNACKA J M. Gene-environment interac⁃
              [4] ZHANG L,HO C T,ZHOU J,et al.Chemistry and biological ac⁃  tions in genome-wide association studies:current approaches and
                    tivities of processed Camellia sinensis teas:a comprehensive re⁃  new directions[J]. Journal of child psychology and psychiatry,
                    view[J].Comprehensive reviews in food science and food safety,  2013,54(10):1120-1134.
                    2019,18(5):1474-1495.                      [20] THOMAS D.Gene-environment interactions in human diseases
              [5] XIA E H,TONG W,WU Q,et al.Tea plant genomics:achieve⁃  [J].Nature reviews genetics,2005,6(4):287-298.
                    ments,challenges and perspectives[J/OL]. Horticulture re⁃  [21] MYLES S,PEIFFER J,BROWN P J,et al.Association map⁃
                    search,2020,7(1):7[2022-03-07].https://doi.org/10.1038/  ping:critical considerations shift from genotyping to experimental
                    s41438-019-0225-4.                              design[J].The plant cell,2009,21(8):2194-2202.
              [6] XIA E H,ZHANG H B,SHENG J,et al.The tea plant genome  [22] GIBSON G. Rare and common variants:twenty arguments[J].
                    provides insights into tea flavor and independent evolution of caf⁃  Nature reviews genetics,2012,13(2):135-145.
                    feine biosynthesis[J].Molecular plant,2017,10(6):866-877.  [23] HAZELETT D J,COETZEE S G,COETZEE G A. A rare
              [7] CHEN J D,ZHENG C M,JIAN Q J,et al.The chromosome-  variant,which destroys a FoxA1 site at 8q24,is associated with
                    scale genome reveals the evolution and diversification after the re⁃  prostate cancer risk[J].Cell cycle,2013,12(2):379-380.
                    cent tetraploidization event in tea plant[J].Horticulture research, [24] GOURAB D,YIP W,IULIANA I,et al.Rare variant analysis
                    2020,7(1):63-73.                                for family-based design[J/OL].PLoS One,2017,8(1):e48495
   39   40   41   42   43   44   45   46   47   48   49