In the context of globalization, the dual pressures of population growth and resources and the environment have driven agriculture to continuously seek new paths to improve overall production efficiency and economic benefits. This study focuses on examining the role of the integrated rice farming model and Huamoxiang rice varieties in improving farmers' economic benefits, with a special focus on the two core economic indicators of planting income and planting profit. Through an analysis method that combines questionnaire surveys and econometric models, the impact of the synergistic effect of the comprehensive rice farming model and the adoption of Huamoxiang varieties on farmers' economic benefits was studied. The results show that the synergistic effect of the two significantly increases the income and profit per unit area of farmers, showing significant income increase effects and economic returns. In addition, land transfer, as an adjusting variable, further optimizes the allocation of land resources and has a positive impact on the economic benefits of integrated rice farming and Huamoxiang varieties. This study provides empirical evidence for the comprehensive rice farming model and the promotion of Huamoxiang varieties, and also provides theoretical support for improving land use efficiency and promoting sustainable agricultural development.