Detection of common viruses causing calf diarrhea and analysis of risk factors
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1.National Key Laboratory of Agricultural Microbiology/College of Veterinary Medicine,College of Animal Sciences and Technology,Huazhong Agricultural University,Wuhan 430070,China;2.The Cooperative Innovation Center for Sustainable Pig Production/Hubei International Science and Technology Cooperation Base of Veterinary Epidemiology,Wuhan 430070,China;3.Hubei Hongshan Laboratory,Wuhan 430070,China

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S858.23

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    Abstract:

    To understand the current epidemiological status and dominant strains of calf diarrhea viruses is important for disease prevention and control.264 diarrheic calves samples (including 58 anal swabs,15 intestinal tissues,and 191 feces) from 41 farms in Hubei,Hunan,Henan,Guangxi,Guizhou,Gansu,Shandong,and Inner Mongolia were collected between November 2021 and October 2023.RT-PCR was used for the detection of bovine rotavirus (BRV),bovine coronavirus (BCoV) and bovine viral diarrhea virus (BVDV).Results showed that the individual positive proportion of BRV,BCoV and BVDV were 14.02% (95% CI: 8.44-16.68),10.23% (95% CI: 6.85-14.53) and 12.12% (95% CI: 10.06-18.80),respectively.The farm positive proportion was 78.05% (95% CI: 62.39-89.44),in which 29.27% (95% CI: 16.13-45.54) had mixed infections.3.42% (95% CI:1.32-5.88) samples were co-infected with both BRV and BCoV,which was the most commonly combination.Furtherly,the distribution of the above three viruses in different regions,ages,seasons and breeds was analyzed.There was a high risk of BRV infection in the northern China,winter and in calves ≤5 weeks old,and BCoV had a high risk of infection in northern China,and both summer and winter.There was no significantly difference BVDV infection in different regions,ages and breeds.The results indicate that the three viruses are prevalent in diarrheal calves across 41 farms in 11 provinces in China,with BRV and BCoV being the main viruses causing calf diarrhea.Their prevalence is influenced by region,season,and age,suggesting that these factors should be considered in prevention and control measures.

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何艳飞,覃城皇,徐肖文,冼茵儿,项志杰,陈颖钰,郭爱珍. Detection of common viruses causing calf diarrhea and analysis of risk factors[J]. Jorunal of Huazhong Agricultural University,2025,44(1):174-182.

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History
  • Received:January 15,2024
  • Revised:
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  • Online: March 03,2025
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