Iron is an essential micronutrient for the normal development of all living things. In particular， cultivating iron-rich seeds through biofortification is an important technical solution to solve the "hidden hunger" of human beings， and chelated iron fertilizer is widely used due to its high efficiency. Therefore， the research and development of novel micronutrient chelators is always a competitive hotspot in the world.The plant-secreted mugineic acids and microbial-secreted siderophores， which can efficiently activate insoluble iron to be bioavailable for plants， are potential novel biochelates， especially microorganisms that can efficiently secrete siderophores have application potential. These novel iron fertilizers can improve the iron nutrition of plants without external iron input， but can activate the rich iron resources in the soil effectively by utilizing the strong chelating property of the active substance of the strain itself， and provide enough bioavailable iron for plants. Therefore， these findings offer applied opportunities for novel biochelates to improve plant iron nutrition and crop yield and sustainable development of agriculture. To further explore and develop those novel and green biochelates， provide new pathways for the development of green intelligent fertilizer， and achieve the sustainable development of agriculture， based on the research progress of the molecular and physiological mechanism of iron uptake and utilization by plants and microorganisms， the research progress and application of novel iron biochelates from plants and microorganisms were reviewed. The study covers the status and causes plant iron deficiency， ways to improve iron nutrition， molecular ecological advantages of iron absorption and utilization by plant root exudates under mechanism Ⅱ， as well as the potential of microbial siderophores to improve plant iron nutrition. It is expected that further research and development will lead to a deeper understanding of the mechanism of these novel biochelates to improve the efficiency of iron nutrient uptake in plants， and provide new ways for realizing the sustainable development of green agriculture. It is expected that further research and development will lead to a deeper understanding of the mechanism of these novel biochelates to improve the efficiency of iron nutrient uptake in plants， and provide new ways for realizing the sustainable development of green agriculture.