Rabies is an ancient zoonosis caused by rabies virus,which infects the central nervous system,causing almost 100% mortality once the clinical symptoms appear. There is no effective treatment available so far. Currently,vaccination is still the most effective way to prevent rabies,so developing rabies vaccines is one of the hot spots in the field of rabies research. With the rapid development of biotechnology,novel rabies vaccines for different uses have been continuously emerged. In this report,the research progress of latest genetic engineering rabies vaccines including inactivated vaccine,attenuated vaccine,nucleic acid vaccine,subunit vaccine,virus-like particle vaccine,oral vaccine etc. is reviewed to grasp the current trend of rabies vaccine and lay the foundation for developing next generation of rabies vaccines.