Misgurnus mohoity (H),Misgurnus bipartitus (N),Misgurnus anguillicaudarus (diploid,B; tetraploid,T) and Paramisgurnus dabryanus (P) were used here to produce 11 kinds of selfing/hybrid offsprings,namely H×H (female×male,HH),N×N (NN),P×P (PP),B×B (BB),P×B (PB),N×H (NH),N×P (NP),P×H (PH),B×P(BP),T×P (TP),and P×T (PT).The culture experiment lasted for 270 d.Total lengths and body weights of the 11 different offsprings were measured at 60d,90d,120d,150d,and 270d,meanwhile the malonaldehyde (MDA) contents were measured at 60 d,90 d,and 120 d.Results obtained here showed that NP kept good growth performance in the entire experimental period.Growth tendencies of PB and PP were poor during the early period from 60d to 90 d,but they began to rise and became good as time went on.In addition,there was no significant difference in growth traits between PB and PP (P>0.05).The body weight of PB at 270 d obviously outweighed other offsprings (P<0.05).The ratios of NP in the 20% of the maximum total length and body weight at 60 d and 90 d exceeded other offsprings.The ratios of TP in the 20% of the maximum and minimum total length and body weight at 270 d were relatively high,while always high for PB in all the sampling times.Both NP and PP with good growth potential had relatively low MDA contents.MDA content of PB rose at 90 d and then stayed high.In conclusion,NP and PP had advantages in growth and immune performance,and PB presented breeding potential in growth traits.