Effects of T01-TPS extracted from Yingshuang (Camellia sinensis) and T09-TPS extracted from Yunnan Dayezhong (Camellia sinensis) on alloxan-induced diabetes mice were studied.Different groups of normal mice and diabetic mice induced by alloxan were administered TPS for 14 days.Fasting blood glucose,weight of body,and immune organs were determined before and after treatment.The glucose tolerance tests were carried out.The results showed that both T01-TPS and T09-TPS significantly decreased the blood glucose level in alloxan-induced mice which was correlated with the dosage of TPS to some degree and increased the glucose tolerance in alloxan-induced mice.Both T01-TPS and T09-TPS improved the index of thymus and spleen.It is indicated that T01-TPS and T09-TPS had remarkable hypoglycemic effect and immune-enhancing activity.The effect of T01-TPS was better than that of T09-TPS.