Two resveratrol synthase genes from different Vitis spp.were isolated and replaced under the control of Ubiquitin promoter,respectively.The vectors were then introduced into japonica rice cultivar ZhongHua 11 through Agrobacterium-mediated gene transformation.Analyses of Southern blot and RT-PCR confirmed that the introduced genes were expressed stably in most of different single-copy gene transformants.Based on the HPLC-MS analysis,a major resveratrol derivative,piceid (resveratrol-glucoside) was detected in the leaves of the single-copy gene transformants with the highest content of 10.26 μg/g fresh weight,1 000-fold more than that of the wild type control.Resuls indicated that resveratrol produced by the exogenously integrated gene might be metabolized into piceid by the endogenous glycosyltransferase.Although these transformants did not show significant resistance towards Magnaporthe grisea,they may have some beneficial effects on human health with the high content of piceid.