Inhibition of tea extracts on glucose uptaking by polarized intestinal Caco-2 cells
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    Abstract:

    The green tea extract (GT),oolong tea extract (OT),black tea extract (BT),Qingzhuan tea extract (QT) and Pu-erh tea extract (PT) were prepared by using water and the effect of them on intestinal glucose uptaking was investigated using polarized Caco-2 intestinal cells.The extracts (0.5 mg/mL)  inhibited glucose uptaking into the intestinal Caco-2 cells under sodium-dependent conditions in the order:GT>OT>BT>QT>PT.Compared with control,GT,OT,BT and QT inhibited significantly glucose-uptaking ( P <0.01),except for PT( P >0.05).Catechin may be the predominant inhibitor in tea and its conversion during manufacturing could affect the glucose-uptake inhibitory activity.

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倪德江,陈玉琼,余志,彼得R.埃利斯,克里斯托P.科尔佩. Inhibition of tea extracts on glucose uptaking by polarized intestinal Caco-2 cells[J]. Jorunal of Huazhong Agricultural University,2013,32(1):116-119.

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  • Received:December 14,2011
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