Field experiments were carried out to investigate the effects of different fertilizer application treatments on the response of biomass dry matter mass and N,P,K uptake and distribution of rice.The results showed that fertilizer increased dry matter mass of brown rice,hull and straw,and N,P,K uptake amount of rice.Compared with CK (without fertilizer),dry matter mass of brown rice,hull and straw of NPK (combined application of N,P and K) treatment increased 1 343,302 and 2 152 kg/hm2,N,P and K uptake amount increased 51.30,11.59 and 76.45 kg/hm2,respectively.N,P,K content of various organs of rice was different.Both N and P content in various organs was in the order of brown rice＞straw＞hull; K content was in the order of straw＞hull＞brown rice.N,P,K distribution in straw increased with fertilizer application,but there was a reverse trend in brown rice.There were similarities and differences of response trend and extent of N,P,K uptake and distribution of different fertilizer treatments.Adjusting fertilizer application can change element distribution in various organs of rice,thus promoting the uptake and circulation of nutrients.This investigation can provide a useful information for high yield production of rice.