The National Key Research and Development Program is the product of the central financial science and technology plan reform during the 13th Five-Year Period.It has gradually become an important channel for China to support major public welfare research，major scientific problems，major generic key technologies and product research and development.In this paper，we take agricultural projects of 11 key projects from 2016 to 2020 as the research object，analyze the distribution of projects in major provinces and three types of units.We select livestock and poultry key project，review from project application and review，project establishment in different fields，research strength composition and trend analysis.Finally，three suggestions are put forward： the first，we should focus on national strategic needs and industrial development trends to foster new projects； the second，we should strengthen cooperation between enterprises，universities and research institutes，build an innovation consortium； the third，we should implement professional management and improve project performance.The above suggestions are intended to provide reference for research institutions and researchers to improve their ability to undertake major national research tasks.