• 首页|编委会|期刊简介|期刊荣誉|投稿指南|联系我们|过刊浏览|在线留言
张英豪,顾泽茂,兰江风.虾应对感染的先天免疫反应研究进展[J].华中农业大学学报,2019,38(3):119-130
虾应对感染的先天免疫反应研究进展
Recent advances in study of immune response of shrimp to pathogen infection:a review
投稿时间:2018-11-02  
DOI:
中文关键词:  甲壳动物  免疫系统  免疫识别  信号通路  效应分子  先天免疫
英文关键词:crustacean  immune system  immunological recognition  signaling pathway  effector molecule  innate immunity
基金项目:国家自然科学基金青年项目(31601209,31502199);湖北省技术创新专项重大项目(2018ABA103);湖北省自然科学基金面上项目(2017CFB550);中央高校基本科研业务费专项(2662018YJ021,2662018JC014)
作者单位E-mail
张英豪 华中农业大学理学院武汉 430070 yhzhang@mail.hzau.edu.cn 
顾泽茂 华中农业大学水产学院武汉 430070
华中农业大学“双水双绿”研究院武汉 430070 
 
兰江风 华中农业大学水产学院武汉 430070
华中农业大学“双水双绿”研究院武汉 430070 
lanjiangfeng@mail.hzau.edu.cn 
摘要点击次数: 232
全文下载次数: 419
中文摘要:
      作为一类重要的无脊椎动物,由于缺少基于“抗体-抗原识别”的特异性免疫机制,虾、蟹等无脊椎动物仅依赖种系基因编码的“模式识别受体”以及相关的免疫调控系统来抵御病原侵袭。以虾、蟹为模型,研究甲壳动物的先天免疫应答机制,不仅可以增补先天免疫知识体系,同时可以为虾蟹病害防控提供有效的理论支撑。本文总结了近年来虾类先天免疫的研究成果,从免疫识别、信号转导、效应分子三个方面简述了目前的研究进展,尤其是对湖北省名特水产品克氏原螯虾(俗称小龙虾)的抗病机制和免疫应答反应作了详细的描述。
英文摘要:
      With the improvement of living standards,people’s demand for aquatic crustacean products such as shrimp and crab is increasing day by day,and the shrimp and crab breeding industry has made great progress recently.At the same time,due to frequent outburst of diseases,shrimp farming industry loses tens of billions of dollars every year.Immune system in vertebrates consists of innate immunity and adaptive immunity,but lack specific adaptive immunity,therefore,vertebrates mainly depend on innate immunity to defend themselves against pathogen invasion.As an important class of invertebrates,shrimp has been found to advance rapidly in the research of innate immunity in the past decade,and shrimp antiviral (especially anti-WSSV immunity) research has made considerable progress.There is no effective platforms,such as cell line and recognized model organism for shrimp and other crustaceans.However,there are still some studies using shrimp or crab as models to study the innate immune response mechanism of crustaceans,which can not only enrich the knowledge of innate immune mechanism,but also provide effective theoretical support for the disease prevention and control of crustaceans.This paper summarizes the research results of innate immunity of shrimps in recent years,and the current research progress in immune recognition,signal transduction,immune defense and so on.Especially,the mechanism of disease resistance of crayfish,a famous and special product in Hubei Province,is described in detail.
查看全文  查看/发表评论  下载PDF阅读器
关闭
版权所有:华中农业大学学报(自然科学版)  
主管单位:教育部 主办单位:华中农业大学 地址:湖北武汉南湖狮子山华中农业大学内
电话:027-87287364 电子邮件:hnlkxb@mail.hzau.edu.cn
您是本站第7307236位访问者  今日一共访问2552次  
技术支持:北京勤云科技发展有限公司