To identify the optimal dietary iron source for largemouth bass （Micropterus salmoides），juvenile fish with an initial body weight （IBW） of （8.60±0.04） g were fed four isonitrogenous，isolipidic，and isoiron diets containing different iron sources，namely，ferrous sulfate （FeSO?），ferrous methionine chelate （Fe-Met），ferrous glycine chelate （Fe-Gly），and ferrous compound amino acids chelate （Fe-CAA） for 10 weeks. The effects of these iron sources on growth performance，blood physiological and biochemical indices，and muscle quality were investigated. The results demonstrated that： （1） The final body weight of the Fe-CAA group［（52.31±0.44） g］ was significantly higher than that of the other three groups （P<0.05）. The condition factor （CF） in the FeSO? and Fe-Gly groups was significantly higher than that in the Fe-Met and Fe-CAA groups （P<0.05）. （2） Serum biochemical parameters and antioxidant capacity were also influenced by the dietary source. High-density lipoprotein （HDL） levels in the FeSO?［（4.14±0.18） mmol/L］ and Fe-CAA［（4.28±0.11） mmol/L］ groups were significantly higher than in Fe-Gly group［（3.61±0.09） mmol/L］ （P<0.05）. Serum aspartate aminotransferase （AST） activity in the Fe-Gly group［（138.33±15.30） U/L］ exceeded that of the FeSO? group［（104.00±4.04） U/L］，while alanine aminotransferase （ALT） activity in the Fe-Met group［（15.00±4.58） U/L］ was significantly higher than in the FeSO? group［（4.67±1.33） U/L］ （P<0.05）. The Fe-CAA group exhibited higher serum superoxide dismutase （SOD） activity［（117.48±2.79） U/mL］ than the Fe-Gly and Fe-Met groups，and the lowest malondialdehyde （MDA） content［（21.30±1.06） mmol/mL］ compared with the other groups （P<0.05）. （3） Muscle SOD activity［（10.44±0.59） U/mg］ in the Fe-CAA group was the highest among all groups，while MDA content［（4.93±0.20） nmol/mg］ in the Fe-CAA group was lower than in the Fe-Met and Fe-Gly groups （P<0.05）. Glutathione （GSH） and catalase （CAT） activities in the FeSO? and Fe-CAA groups exceeded those in the Fe-Met and Fe-Gly groups （P<0.05）. Additionally，Fe-CAA exhibited a higher total antioxidant capacity［T-AOC，（1.79±0.04） mmol/L］ than the Fe-Gly and Fe-Met groups （P<0.05）. （4） Fe-CAA also showed significantly elevated trypsin activity［（1 116.62±138.90） U/mg］ compared to the FeSO? and Fe-Met groups （P<0.05）. In conclusion，Fe-CAA demonstrated advantages in enhancing growth performance and antioxidant capacity compared to the other three iron sources，which could be suggested as the first choice of iron source in largemouth bass diet.