Slow/controlled release fertilizer can enhance the nutrient use efficiency，which is an important technology to increase nutrient utilization rate，and metal organic frameworks （MOF） provided an alternative option for the development of slow/controlled release fertilizer. MOF，comprised of organic ligands and metal ions/metal clusters via coordinative bonds are highly porous，crystalline materials，and the tunable porosity，chemical composition，size and shape，and easy surface functionalization make this large family more and more popular. There has been a growing interest over the last decades in the design of engineered MOF with controlled sizes for a variety of applications in the fields of chemistry，materials science，medicine，biosensor etc.，but MOF’s application in agricultural science is in initial stage. MOF composition and structure as well as the synthesis approaches were elucidated，and the applications in main fields including in agricultural science were summarized，in particular，the potentials in the application as a new type of slow/controlled release fertilizer was addressed； then challenges in MOF development for slow/controlled release fertilizer were discussed. Multi-nutrient elements could be combined in MOF by directional design in molecular level according to the nutrient demand of crops，which provided new technical support for the development of slow/controlled release fertilizer.