Potato (Solanum tuberosum L.) is the world’s largest non-cereal food crop and plays an important role in the global economy and food security. Tubers are economic organs and reproductive organs of potato. They store a large amount of starch,and their development process is regulated by sugar signals. Sugar signal regulates potato tuber morphogenesis and sink-source relationship. This article summarizes the progress on plant sugar signal pathway,sugar signal regulating potato tuber morphogenesis,source-sink relation and its cross-talk with photoperiod,plant hormones and other signal pathways. On this basis,the model of sugar signal regulating potato tuber development was proposed to provide a reference for further elucidating the mechanism of sugar signal regulating potato tuber development.