Abstract:The green tea extract (GT),oolong tea extract (OT),black tea extract (BT),Qingzhuan tea extract (QT) and Pu-erh tea extract (PT) were prepared by using water and the effect of them on intestinal glucose uptaking was investigated using polarized Caco-2 intestinal cells.The extracts (0.5 mg/mL) inhibited glucose uptaking into the intestinal Caco-2 cells under sodium-dependent conditions in the order:GT＞OT＞BT＞QT＞PT.Compared with control,GT,OT,BT and QT inhibited significantly glucose-uptaking ( P <0.01),except for PT( P >0.05).Catechin may be the predominant inhibitor in tea and its conversion during manufacturing could affect the glucose-uptake inhibitory activity.