To address the problems of high intensification， low operational efficiency， high labor intensity， and significant spray liquid waste in intensive pig farming in China， a remote-controlled electric spray disinfection machine was designed and developed based on the disinfection and epidemic prevention requirements of large-scale pig farms， combined with numerical simulation and prototype tests. The machine features a compact structure with overall dimensions of 0.8 m × 0.8 m × 1.1 m， a horizontal spray width of 3 m， and a vertical spray height of 3 m， making it suitable for operation in 1.2-1.5 m wide passages within pig houses. Simulation results demonstrate that the total droplet deposition rate is positively correlated with spray pressure. Higher spray pressure increases the initial kinetic energy and breakup of droplets， producing finer particles with smaller sizes， thereby improving penetration， uniformity， and deposition rate. Prototype tests results indicate that at an operating pressure of 10 MPa， the volume median diameter of droplets is 53.6 μm， and the average spray liquid adhesion rate reaches 78.98%， significantly higher than the 42.6% achieved by traditional manual spraying. The designed machine enables efficient and uniform all-around disinfection in pig houses， providing high-efficiency， safe， and practical technical equipment for disinfection and epidemic prevention in large-scale pig farms.