Page 49 - 《华中农业大学学报》2020年第6期

第 ６ 期 祝友朋 等:不同营养类型植物病原真菌次生代谢产物合成基因簇的差异性研究 ４ ３

stract ) ． dahliae [ J ] ．Jian g suj ournalofa g riculturescience , ２０１９ , ３５
[ ２１ ]叶美金, 郭海霞, 杨财容, 等 ． 渐绿木霉基因组中 PKS 和 NRPS ( ６ ): １２９９Ｇ１３０７ ( inChinesewithEn g lishabstract ) ．
[ ２４ ]赵中涛 ． 真菌生长发育和致病相关基因家族的比较和进化基因
基因的 多 样 性 分 析 [ J ] ． 分 子 植 物 育 种, ２０１８ , １６ ( １４ ): ４６０７Ｇ
４６１３．YE MJ , GUO H X , YANGCR , etal．Anal y sisofPKS 组学研究[ D ] ． 杨 凌: 西 北 农 林 科 技 大 学, ２０１４．ZHAO Z T．
andNRPSg enediversit y inTrichodermaviridescens [ J ] ．MoＧ Ph y lo g eneticandcom p arativeg enomicanal y sisoffun g al g ene
lecular p lantbreedin g , ２０１８ , １６ ( １４ ): ４６０７Ｇ４６１３ ( in Chinese famil yrelatedtofun g aldevelo p mentandp atho g enicit y [ D ] ．
withEn g lishabstract ) ． Yan g lin g : NorthwestA&F Universit y , ２０１４ ( inChinesewith
[ ２２ ]魏鹏霖, 张鹏, 李伟, 等 ． 黄曲霉分生孢子色素合成基因 p ks１ 的 En g lishabstract ) ．
鉴定及其对生长发育和侵染性的影响[ J ] ． 微生物学报, ２０１９ , [ ２５ ]陈相永, 陈捷胤, 肖红利, 等 ． 植物病原真菌寄生性与分泌蛋白
５９ ( ５ ): ９６５Ｇ９７７．WEIPL , ZHANGP , LIW , etal．IdentificaＧ 组 CAZ y mes的比较分析[ J ] ． 植物病理学报, ２０１４ , ４４ ( ２ ): １６３Ｇ
tionofconidialp i g ments y ntheticg enep kslanditseffecton １７２．CHENXY , CHENJY , XIAO H L , etal．Thecom p araＧ
develo p mentandp atho g enicit y inAs p er g illus f lavus [ J ] ．Acta tiveanal y sisofsecreted CAZ y mesinp h y to p atho g enicfun g i
microbiolo g icasinica , ２０１９ , ５９ ( ５ ): ９６５Ｇ９７７ ( inChinesewith withdifferentlifest y le [ J ] ．Actap h y to p atholo g icasinica , ２０１４ ,
En g lishabstract ) ． ４４ ( ２ ): １６３Ｇ１７２ ( inChinesewithEn g lishabstract ) ．
[ ２３ ]姚传飞, 张昕, 邓晟, 等 ． 大丽轮枝菌微菌核发育相关基因 VdＧ [ ２６ ] TIANB , XIEJ , FUY , etal．Acosmo p olitanfun g al p atho g enof
PKS 的功能分析[ J ] ． 江苏农业学报, ２０１９ , ３５ ( ６ ): １２９９Ｇ１３０７． dicotsado p tsanendo p h y ticlifest y leoncerealcro p sandp roＧ
YAO CF , ZHANG X , DENGS , etal．Functionalanal y sisof tectsthemfrom ma j orfun g aldiseases [ J / OL ] ．TheISME j ourＧ
VdPKSrelatedtomicrosclerotiadevelo p mentofVerticillium nal , ２０２０．htt p s :// doi．or g / １０．１０３８ / s４１３９６Ｇ０２０Ｇ００７４４Ｇ６．

Differencesing eneclustersofs y nthesizin g secondar ymetabolites
of p lant p atho g enicfun g iwithdifferentnutritionalt yp es

,
ZHU You p en g HANChan g zhi
TheYunnanProvinceKe yLaborator yo fForestDisasterWarnin gandControl ,
Colle g eo fBiodiversit yConservation , SouthwestForestr yUniversit y Kunmin g６５０２２４ , China
,

Abstract Twent y Ｇtwofun g iwithwholeg enomese q uencep ublishedandtheantiSMASHdatabase
wereusedtoclassif y andannotatethe g eneclustersofs y nthesizin g secondar ymetabolitesof p lant p athoＧ
g enicfun g iwithdifferentnutritionalt yp esinordertoclarif y theroleofsecondar ymetabolitesof p lant
p atho g enicfun g iwithdifferentnutritionalt yp esininfectin gp lantsandthedifferencesing eneclusters．
Theresultsshowedthatthet yp eandnumberof g eneclustersofs y nthesizin gsecondar ymetabolitesof
hemiＧbiotro p hsandnecrotro p hsfun g iwerehi g herthanthatofbiotro p hsfun g i．Theresultsoffurther
anal y zin g theg eneclustersofs y nthesizin gsecondar y metabolitesofnonＧribosomal p e p tides y nthetase ,
p ol y ketides y nthaseandter p eneshowedthatthenumberofNRPSg eneclusters , PKSg eneclustersand
ter p eneg eneclustersinhemiＧbiotro p hsandnecrotro p hsp atho g enicfun g iwerehi g herthanthatin
biotro p hsp atho g enicfun g iaswell．Itwill p rovideanim p ortanttheoreticalbasisforfurtheranal y zin g the
functionoftheg eneclusterofs y nthesizin g secondar ymetabolitesofdifferenttro p hict yp esoffun g iand
identif y in gnewdru g tar g ets．Anal y zin g theg eneclustersofs y nthesizin gsecondar ymetabolitesinfun g i
andclarif y in g thedifferencesing eneclustersofs y nthesizin g secondar ymetabolitesofdifferentnutrition
t yp esoffun g iisconducivetothebetterdevelo p mentofmedicamentsfor p reventin gandcontrollin gnoＧ
velactiontar g etsof p lantdiseases．
Ke y words p lant p atho g enicfun g i ; nutritiont yp es ; eneclustersofs y nthesizin g secondar ymetaboＧ
g
lites ; immunedefenseres p onse

( 责任编辑: 张志钰)