Aiming at the existing freshwater fish fish body dissection device is mainly hand-feeding, single-machine operation, processing efficiency is low, can not meet the mechanisation, automation of fish body dissection processing needs, etc., this paper takes Hypophthalmichthys moritrix as the object of study, carries out the research on the key components of the clamping-type Hypophthalmichthys moritrix body dissection device, and test-produces the clamping-type Hypophthalmichthys moritrix body dissection device, and test validates it. The experimental verification was carried out. The Hypophthalmichthys moritrix body dissection device consists of a frame, a fish conveyor, a fish body clamping mechanism, a fish body dissection mechanism, and a cleaning mechanism; through the compression test of the fish body, we obtained the minimum limiting pressure of the fish body; through the analysis of the force of the fish body clamping and conveying process and the dissection process, we explored the conditions of satisfying the clamping and conveying process as well as the magnitude of the force of the knife discs with different rotational directions on the fish. Taking Hypophthalmichthys moritrix acceptability score and cutting loss rate as evaluation indexes, a one-way test was carried out on the influencing factors such as initial spacing of clamping rollers, Cutterhead sectioning high, rotating speed of cutter, etc., to explore the effects of the factors on the cutting effect of Hypophthalmichthys moritrix. Through orthogonal test, it was determined that the order of the factors affecting the fish body cutting effect was: Cutter speed of cutter > Cutter sectioning high > Initial spacing of pinch rollers; when the initial spacing of pinch rollers was 20mm, the rotating speed of cutter sectioning high was 135mm, and the rotating speed of cutter speed was 1400r/min, the Hypophthalmichthys moritrix body was smooth in section, and the integrity of the flesh was high, and the average value of the acceptability score was 9.48, and the rate of loss of sectioning was 0.11%, and the processing efficiency can be up to 8.0 fish/min. The results of this paper can provide a reference for the research and development of bulk freshwater fish body dissection device and the design of automated pre-treatment processing line for freshwater fish.