Abstract： [Aim] Continuously monitoring of the susceptibilities of Cnaphalocrocis medinalis field populations to insecticides is an important measure for the control and resistance management of C. medinalis. The present study aims to detect the susceptibilities to commonly used insecticides of C. medinalis field populations in Hubei, Hunan, Jiangxi, Anhui and Henan provinces. [Methods] The leaf-dipping method was used to detect susceptibilities to seven insecticides of C. medinalis field populations in Chibi, Wuxue, Wuhan, Xiaogan, Huanggan, Changsha, Nanchang, Pingxiang, Hefei and Xinyang in 2015~2019. In addition, cluster and regression analyses are performed on the detected data. [Results] 1. There were significant differences among the toxicities of seven insecticides against C. medinalis field populations. The order of the toxicity of seven insecticides is fluorobenzamide ≥ abamectin ≥ spinetoram > chlorantraniliprole ≥ indoxacarb > cyantraniliprole > chlorpyrifos. 2. No significant susceptibility difference was detected among different populations of C. medinalis. 3. There was significant difference between years. Significant changes of sensitivities in different years were found among some populations to chlorpyrifos, chlorantraniliprole, indoxacarb and cyantraniliprole. The susceptibility levels of Chibi and Changsha populations of C. medinalis to chlorpyrifos decreased by 2.3- and 4.1-fold from 2015 to 2016. The susceptibility levels of Chibi and Changsha populations to chlorpyrifos increased by 2.1- and 4.9-fold from 2016 to 2019. The susceptibility levels of Chibi, Wuxue and Xiaogan populations to chlorantraniliprole decreased by 2.6- and 7.3-fold from 2015 to 2019. The susceptibility level of Wuxue population to indoxacarb decreased by 4.2- and 4.7-fold from 2015 to 2018. The susceptibility levels of Wuxue and Changsha population to cyantraniliprole decreased by 2.2- and 6.7-fold from 2015 to 2018. [Conclusion] The susceptibility levels of C. medinalis field populations to chlorantraniliprole and other insecticides in central China are decreasing significantly, so that the resistance management for these insecticides is very important currently. Abamectin, spinetoram and cyantraniliprole can be preferentially recommended for the control of C. medinalis, under a rotation manner.