食品安全检验和临床诊断与人们健康息息相关,如何有效地提高食品安全检测和临床诊断能力一直是各界所关注的重点。其中,快速检测作为一种高效方便的检测方式被认为是突破这一难题的重要手段。磁弛豫(Magnetic Relaxation Switching, MRS) 生物传感器因其优良的分析性能、简便的分析流程,已经成为快速检测的新方法、新工具。为提高磁弛豫传感器的性能,国内外研究者在发掘有效的信号转化机制、构建新型纳米磁探针、开发高效的信号放大系统以及提高传感器稳定性等方面开展了大量的研究工作,有力地推动了该技术在快速检测领域的发展。本文围绕磁弛豫生物传感器的传感机制、最新研究进展和应用领域展开了综述。
Food safety analysis and clinical diagnosis are closely related to people"s health. How to improve the ability of food safety analysis and clinical diagnosis have always been the focus of all over the world. As an efficient and convenient method, rapid detection has been considered as an important means to break through this problem. And magnetic relaxation switching (MRS) biosensor has become a new tool for rapid detection due to its excellent analytical performance and simple analysis process, which has been used in the field of public health. In order to improve the performance of the MRS biosensors, researchers have done a lot of works such as exploring effective signal conversion mechanism, constructing new nanometer magnetic probe, developing efficient signal amplification system and improving the stability of the sensor, which has greatly promoted the development of rapid detection. In this paper, different sensing mechanisms, recent research progress and applications of MRS biosensors are reviewed.