Two types of cadmium （Cd） contaminated soils in Xichuan County，Henan Province were collected to study the feasibility of using bio-organic fertilizers to treat cadmium contaminated soils and the effectiveness of remediating heavy metal pollution in soil.6 treatments of fertilization including CK （without applying any materials），NPK （conventional application of NPK fertilizer），NPK+0.5% OF （conventional fertilization + 0.5% commercial organic fertilizer），NPK+1% OF （NPK + 1% commercial organic fertilizer），NPK+0.5% BF （NPK + 0.5% bio-organic fertilizer），and NPK+1% BF （NPK + 1% bio-organic fertilizer） were set up.The content of total cadmium in the soil，the chemical forms of cadmium in the soil，and the content of cadmium in the roots and seeds of maize were measured before and after planting.The results showed that the effect of NPK+1% BF was the best，and the content of available cadmium in two types of soil under NPK+1% BF decreased by 19.74% and 7.09% compared to that under NPK+1% OF.The application of organic materials reduced the content of cadmium in the weakly acid-extractable state in soil and increased the content of cadmium in the residual state.The content of cadmium in the weakly acid-extractable state in soil under NPK+1.0% BF decreased by 11% compared to that under CK，while the content of cadmium in the residual state increased by 16%.The application of organic materials significantly reduced the content of cadmium in the roots and seeds of maize，with the NPK+1.0% BF having the best effect.Compared with NPK treatment，the content of cadmium in roots and seeds of maize in soil I decreased by 34.41% and 31.59%，respectively.It is indicated that applying bio-organic fertilizers in cadmium contaminated soil can significantly reduce the content of available cadmium in the soil，promote the transformation of cadmium in the weakly acid-extractable state to cadmium in the residual state，and reduce the hazards of cadmium.The content of cadmium in roots and seeds of maize significantly decreases，and bio-organic fertilizer is superior to commercial organic fertilizer in terms of the comprehensive effect.