In order to contain COVID-19,Wuhan has been locked down since January 23,2020,leaving a profound impact on the operation of the agricultural product supply chain. The author conducted a telephone interview survey on 107 agricultural product suppliers in Wuhan during the epidemicand analyzed the impact of the epidemic situation before and after Wuhan’s lockdown on the agricultural product supply chain from business status,purchase situation,sales situation and future expectations of the merchant. The analyses lead to the following conclusions. First of all,The epidemic has a great impact on the supply chain of agricultural products in Wuhan,and the lockdown of Wuhan has exacerbated the impact. In addition,the lockdown of Wuhan has different impacts on the closure of different types of suppliers,with the greatest impact on grain and oil suppliers,followed by fruits and vegetables suppliers,and with the least impact on meat and eggs suppliers. What’s more,the lockdown of Wuhan has led to a narrowing of the purchase channels of agricultural product suppliers and their increased reliance on wholesalers. Moreover,the lockdown of Wuhan had the greatest impact on the sales of fruits,vegetables,meat,egg and milk products,and the least impact on grain and oil products. Finally,different types of suppliers have different expectations after the epidemic. Among them,meat,egg and milk suppliers choose to remain in the original industry with the highest proportion,followed by fruit and vegetable suppliers and grain and oil suppliers. Therefore,under the background of normalized epidemic prevention and control,policy suggestions are put forward to ensure the normal operation of the agricultural product supply chain,including assisting resumption of work,broadening agricultural product supply channels,strengthening the linkage between supply and demand and adjusting supplier expectations.