Abstract:Substantial ethics in industrialization of genetically modified crops (GMC) is to study whether it should do or not, while procedural ethics is to study how it should do. In the current situation, ethical research in industrialization of GMC should be shifted from substantial ethics to procedural ethics, and this shift has its theoretical rationality and practical rationality. We should establish procedural ethics on basis of ethical governance, such as clearing the subjects of ethical governance in industrialization of GMC, studying foundations of it, establishing main contents of it, and building mechanism of discourse ethics of it , which contributes to scientific and effective decision-making, and standardized management in it, and which brings more well-being to human.