This paper selects thirty-nine indices to analyze the sustainable development of thirteen cites in Hunan province by means of factor analysis.Factors affecting the sustainable development of Hunan province are divided into four kinds and the variables of weighed synthetic factor scores are obtained by means of cluster analysis.The result shows that there are great differences among the above 13 selected cities in the sustainable development and these 13 cities can be classified into four grades.Finally this paper analyzes the regional differences among index scores of every city in each grade respectively,and proposes some corresponding measures.