Abstract:Sci-tech translation propels forward the science and culture of mankind.During the late Ming Dynasty and the early Qing Dynasty,the sci-tech translation became the mainstream of the translation activity and exerted a great influence on China's society.This climax of sci-tech translation not only germinated the modern science,but also pounded the confined ideological field of China at that time.In more than 100 years,the translators at home and abroad left their valuable translation works and useful translation thoughts,all of which are still in use today.Making analyses and comments on the translation activity,this paper probes into its influence and effect in sci-tech translation field.